姓名：

张睿

性别：

男

职称：

副教授

所在部门：

放射卫生

最后学历：

研究生

最高学位：

博士

Email:

zhangrui625827@jlu.edu.cn

所在学科业：

放射卫生学

研究方向：

1.新型X-射线敏化剂的构建及在肿瘤治疗中的应用；

2.肿瘤的早期诊断

讲授课程：

放射化学

放射化学实验

教育经历：

2016.07-2020.07 香港城市大学化学系化学专业，理学博士

2005.08-2009.07 天津工业大学化学工程与技术学院化学工程与技术专业，工学学士

工作经历：

2020.09 -至今 吉林大学公共卫生学院，副教授

2009.08-2016.06 天津大学化学系，科研助理

科研项目：

1. 吉林大学海外博士A类人才启动项目，2020-2024，35万，主持人。

2. 吉林省自然科学基金，“靶向有机纳米线阵列的构建及其和单细胞作用的研究”，No.20220101193JC2022-2025,10万，主持人

3. 横向课题“纳米材料在制药行业的推广应用”，22万，2023-2028。

学术论文：

1. R. Zhang*, M. Jia, H. Lv, M. Li, G. Ding, G. Cheng, J. Li*. Assembling Au8 clusters on surfaces of bifunctional nanoimmunomodulators for synergistically enhanced low dose radiotherapy of metastatic tumor.Journal of Nanobiotechnology. 2024, 22 (20), 1-17. (IF= 10.2)

2. R. Zhang, Z. Zhu, H. Lv, F. Li, S. Sun, J. Li*, C.-S. Lee*. Immune Checkpoint Blockade Mediated by Small-molecule Nanoinhibitor Targeting the PD-1/PD-L1 Pathway Synergizes with Photodynamic Therapy to Elicit Antitumor Immunity and Antimetastatic Effects on Breast Cancer. Small. 2019, 1903881 (IF=13.3).

3.  R. Zhang, Y. Guan, Z. Zhu, H. Lv, F. Li, S. Sun, J. Li*. Multifunctional Tetracene/Pentacene Host/Guest Nanorods for Enhanced Upconversion Photodynamic Tumor Therapy. ACS Appl. Mater. Interfaces 2019, 11, 37479−37490. (IF = 9.5)

4.  R. Zhang, G. Cheng, S. Liu, H. Lv, J. Li*. A four-in-one pure nanomedicine for synergistic multi-target therapy against breast cancer. J. Mater. Chem. B, 2021, 9, 8809. (IF=7.0).

5.  R. Zhang, Y. Wan, H. Lv, F. Li, C. -S. Lee*. DTX@VTX NPs synergy PD-L1 immune checkpoint nanoinhibitor to reshape immunosuppressive tumor microenvironment for enhancing chemoimmunotherapy. J. Mater. Chem. B, 2021, 9, 7544. (IF=7.0).

6.  M. Li, G. Cheng, R. Zhang*, J. Li*. Simple Multifunctional PTX@Ce6 Nanomedicine for Eradicating Tumor in the Combination of Photodynamic Therapy and Metronomic Chemotherapy. ACS Omega 2022, 7, 48372.

7. R. Zhang*, G Cheng, M. Li, H. Lv, J. Li*. Pentacene Nanorods as Effective Photosensitizers for Photodynamic Therapy of Tumors via Singlet Fission. Part. Part. Syst. Charact. 2023, 40, 2200174.

8. R. Zhang, B. Zhang, Y. Liu, S. Sun, Preparation of 3D graphene networks and a C dot grafted graphene hybrid by new methods for improving the photovoltaic performance of CdS/CdSe quantum dot sensitized solar cells J. Mater. Chem. C, 2016, 4, 1633-1644. (IF=6.4) 

9. R. Zhang, Y. Liu, S. Sun, Facile synthesis of water-soluble ZnS quantum dots with strong luminescent emission and biocompatibility. Applied Surface Science 2013, 282,960（IF=6.7）.

10. R. Zhang, B. Zhang S. Sun, Preparation of high-quality graphene with a largesize by sonication-free liquid-phase exfoliation of graphite with a new mechanism. RSC Adv., 2015, 5, 44783–44791.

10. R. Zhang, Y. Liu, L. Yu, Z. Li, S. Sun,Preparation of high-quality biocompatible carbon dots by extraction, with new thoughts on the luminescence mechanisms. Nanotechnology 2013, 24, 225601.

11. R. Zhang, Y. Liu, S. Sun, Preparation of highly luminescent and biocompatible carbon dots using a new extraction method. J Nanopart Res 2013, 15, 2010.

12. R. Zhang, Y. Liu, S. Sun, Synthesis and characterization of high-quality colloidal Mn2+-doped ZnS nanoparticles. Optical Materials 2012, 34, 1788–1794.

13. R. Zhang, W. Xiang*, Preparation and luminescent characteristics of Sr3RE2(BO3)4:Dy3+ (RE = Y, La, Gd) phosphors for white LED. Journal of Alloys and Compounds 2011, 509, 1197–1200.(IF=6.2)