所在学科专业：

社会医学与卫生事业管理

研究方向：

Health and related factors, mental health, Community Health Services, Epidemiology of Chronic Diseases

讲授课程：

《社会医学》
《卫生服务评价》
《健康教育与健康促进》

教育经历：

2005.09 ～ 2008.06    吉林大学   博士
2002.09 ～ 2005.06    吉林大学   硕士
1997.09 ～ 2002.07    吉林大学   学士

工作经历：

2016.09 ～Now      吉林大学公共卫生学院      副教授
2010.09 ～ 2011.10  University of Saskatchewan           访问学者                  

2008.07 ～ 2016.09  吉林大学公共卫生学院      讲师

2006.09 ～ 2008.06  吉林大学公共卫生学院      助教

科研项目：

 辽宁省心理健康素养调查抽样及数据处理分析（负责人）

 吉林省0-6岁儿童营养健康状况及6-24月龄食用营养包婴幼儿营养改善状况研究（负责人）

 基于中国家庭追踪调查探讨中国成人生命质量现状及影响因素（负责人）

 丰满区和德惠市社区居民精神卫生状况随访调查（负责人）

 Analysis on the status and influence factors of high risk of maternal mortality in Jilin Province. 2016.07-2017.06. [principal]

 Baseline survey on health theme parks and fitness trails project in Jilin Province. 2016.05-2016.10.  [principal]

 Survey on the physiological and psychological health status, stress, and utilization of mental health service resources in Jilin University teachers, 2012.04-now. Sponsored by Jilin University. [principal]

 Epigenetic epidemiological study on the relationship between phospholipase A2 gene family DNA methylation and schizophrenia, 2010.01-2012.12. Sponsored by National Natural Science Foundation of China. [participant]

 Genetic epidemiological study on the disease-related marker proteins and candidate genes of schizophrenia. , 2010.01-2012.12. Sponsored by National Natural Science Foundation of China. [participant]

 Study on the role of DNA methylation in the pathogenesis of schizophrenia, 2009.01-2011.12. Sponsored by National Natural Science Foundation of China. [participant]

 The role of glutenin in pathogenesis of neurodevelopmental disorders, 2008.01-2010.12. Sponsored by National Natural Science Foundation of China. [participant]

 Survey on the use of tobacco in Chinese young women, 2008.06-2008.12. Sponsored by USA National Institutes of health. [participant]

学术论文：

第一作者和通讯作者论文：

 Yuan, X.; Kou, C.; Zhang, M.; Ma,W.; Tang, Z.; Sun, H.; Li,W. Injury and Poisoning Mortality Trends in Urban and Rural China from 2006 to 2020 Based on Age-Period-Cohort Analysis. Int. J. Environ. Res. Public Health 2022, 19, 7172. https://doi.org/10.3390/ ijerph19127172

 Li W, Sun H, Xu W, Ma W, Yuan X, Wu H, Kou C. Leisure activity and cognitive function among Chinese old adults: The multiple mediation effect of anxiety and loneliness. J Affect Disord. 2021 Nov 1;294:137-142. doi: 10.1016/j.jad.2021.07.051. Epub 2021 Jul 17. PMID: 34298217.

 Xu W, Sun H, Zhu B, Yu X, Niu Y, Kou C, Li W. The prevalence of depressive symptoms and its determinants among adults in mainland China: Results from a national household survey. J Affect Disord. 2021 Feb 15;281:220-227. doi: 10.1016/j.jad.2020.12.009. Epub 2020 Dec 9. PMID: 33333476.

 Li W, Sun H, Xu W, Ma W, Yuan X, Niu Y, Kou C. Individual Social Capital and Life Satisfaction among Mainland Chinese Adults: Based on the 2016 China Family Panel Studies. Int J Environ Res Public Health. 2021 Jan 8;18(2):441. doi: 10.3390/ijerph18020441. PMID: 33429886; PMCID: PMC7827718.

 Xu W, Sun H, Zhu B, Bai W, Yu X, Duan R, Kou C, Li W. Analysis of Factors Affecting the High Subjective Well-Being of Chinese Residents Based on the 2014 China Family Panel Study. Int J Environ Res Public Health. 2019 Jul 18;16(14):2566. doi: 10.3390/ijerph16142566. PMID: 31323796;

 Li Y, Kou C, Bai W, Hua W, Yu W, Song Y, Liu X, Li W. Trends in Diabetes Mortality by Gender in Urban and Rural Areas in China From 2003 to 2012: An Age- Period-Cohort Analysis. Asia Pac J Public Health. 2019 Apr;31(3):238-245. doi: 10.1177/1010539519841288. Epub 2019 Apr 9. PMID: 30966779.

 Wang M, Kou C, Bai W, Song Y, Liu X, Yu W, Li Y, Hua W, Li W. Prevalence and correlates of suicidal ideation among college students: A mental health survey in Jilin Province, China. J Affect Disord. 2019 Mar 1;246:166-173. doi: 10.1016/j.jad.2018.12.055. Epub 2018 Dec 19. PMID: 30583141.

 Li W, Kou C. Prevalence and correlates of psychological stress among teachers at a national key comprehensive university in China. Int J Occup Environ Health. 2018 Jan-Apr;24(1-2):7-16. doi: 10.1080/10773525.2018. 1500803. Epub 2018 Jul 26. PMID: 30047833; PMCID: PMC6225434.

 Li W, Meng X, Xu Z, Yu Q, Shi J, Yu Y, D'Arcy C, Huang Y, Kou C. Prevalence, correlates of major depression: A mental health survey among undergraduates at a mainland Chinese university. Asia Pac Psychiatry. 2016 Sep;8(3):206-14. doi: 10.1111/appy.12202. Epub 2015 Jul 15. PMID: 26178524.

 Li W, Zhou N, Yu Q, Li X, Yu Y, Sun S, Kou C, Chen DC, Xiu MH, Kosten TR, Zhang XY. Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population. Am J Med Genet B Neuropsychiatr Genet. 2013 Sep;162B(6):538-45. doi: 10.1002/ajmg.b.32183. Epub 2013 Jul 7. PMID: 23832605.

 Li WJ, Kou CG, Yu Y, Sun S, Zhang X, Kosten TR, Zhang XY. Association of catechol-O-methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population. Am J Med Genet B Neuropsychiatr Genet. 2012 Jun;159B(4):370-5. doi: 10.1002/ajmg.b.32038. Epub 2012 Feb 21. PubMed PMID: 22354729;

 Li W, Tao R, Zhang X, Ju G, Shi J, Liu S, Wang Z, Jin S, Guo Y, Wei J. A family-based study of genetic association of the PTGDS gene with schizophrenia in a Chinese population. Psychiatr Genet. 2008 Apr;18(2):99. doi: 10.1097/YPG.0b013e3282f97e1c. PMID: 18349703.

 Li W, Wei J, Zhou DF, Tan YL, Cao YL, Zhang XY, Wu G, Kosten TA, Kosten TR. Lack of association between the BDNF C270T polymorphism and schizophrenia in a Chinese Han population. Schizophr Res. 2007 Dec;97(1-3):297-8. Epub 2007 Jul 31. PubMed PMID: 17669628.

 长春市在校女学生吸烟现状及影响因素. 医学与社会. 2013, 26(12):5-7.

 PCYT1B基因多态性与精神分裂症的关系.中华疾病控制杂志,2008,12(4):321-323.

 PCYT1A基因多态性与精神分裂症的关系.吉林大学学报（医学版）,2007,33(5):883-885

 医院感染的预防和控制，中华医院感染学杂志,　2005，15(5):550-552.

 非胰岛素依赖型糖尿病易感基因定位研究进展，吉林大学学报（医学版）,　2004，30(6):991-993.

共同作者论文：

 Li Y, Bai W, Zhu B, Duan R, Yu X, Xu W, Wang M, Hua W, Yu W, Li WJ, Kou C. Prevalence and correlates of poor sleep quality among college students: a cross- sectional survey. Health Qual Life Outcomes. 2020 Jul 1;18(1):210.

 李晶华,张馨遥,张秀敏,李文君,李卉,刘娅.以实践技能提高为导向的公共卫生硕士专业学位“卫生事业管理学”教学实践及探讨[J].高校医学教学研究(电子版),2019,9(01):34-37.

 Zhou N, Yu Q, Li X, Yu Y, Kou C, Li W, Xu H, Luo X, Zuo L, Kosten TR, Zhang XY. Association of the dopamine β-hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Hum Psychopharmacol. 2013 May;28(3):230-7. doi: 10.1002/hup.2311. Epub 2013 Apr 5. PMID: 23559427.

 Han H, Yu Y, Shi J, Yao Y, Li W, Kong N, Wu Y, Wang C, Wang S, Meng X, Kou C. Associations of histone deacetylase-2 and histone deacetylase-3 genes with schizophrenia in a Chinese population. Asia Pac Psychiatry. 2013 Mar;5(1):11-6. doi: 10.1111/j.1758-5872.2012.00205.x. Epub 2012 Jul 18. PMID: 23857786.

 HDAC8基因多态性与中国北方汉族精神分裂症的关联性分析. 吉林大学学报：医学版，2012,38（6）：1164-1167.

 Hui L, Zhang X, Huang XF, Han M, Fernandez F, Yu Y, Sun S, Li W, Chen DC, Xiu MH, Kosten TR, Zhang XY. The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia. J Psychiatr Res. 2012 Jun;46(6):733-7. doi: 10.1016/j.jpsychires.2012.02.016. Epub 2012 Mar 24. PMID: 22445279.

 Yang YQ, Sun S, Yu YQ, Li WJ, Zhang X, Xiu MH, Chen da C, De Yang F, Liu H, Li C, Kosten TR, Zhang XY. Decreased serum brain-derived neurotrophic factor levels in schizophrenic patients with tardive dyskinesia. Neurosci Lett. 2011 Sep8;502(1):37-40. doi: 10.1016/j.neulet.2011.07.020. Epub 2011 Jul 20. PubMed PMID:21798311.

 Zhang XY, Yu YQ, Sun S, Zhang X, Li W, Xiu MH, Chen da C, Yang FD, Zhu F, Kosten TA, Kosten TR. Smoking and tardive dyskinesia in male patients with chronic schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Aug 15;35(7):1765-9. doi: 10.1016/j.pnpbp.2011.06.006. Epub 2011 Jun 23. PubMed PMID: 21723906.

 锦灯笼宿萼提取物体外抗菌作用研究，天然产物研究与开发,　2006，18(2)

 贡菜提取液的抗病原性真菌活性研究，天然产物研究与开发2005，17(4)

著作教材：

《公卫医师应试指导（2014版）》，中国协和医科大学出版社，参编。

社会兼职：

吉林省预防医学会社会医学专业委员会，委员。